Immunochemistry and Lung Cancer: Application in Diagnosis, Prognosis and Targeted Therapy
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چکیده
Immunochemistry is now an established ancillary technique in lung cancer diagnosis. Not only does it help in supporting the morphological diagnosis of malignancy, but its role now extends to the determination of cell lineage, ascertaining the primary site of tumour origin and contributing to decisions on prognosis and treatment. Early detection and confirmation of lung cancer facilitate early treatment decisions. Lung cancer management now has a multidisciplinary approach which includes cytopathologists and clinicians. Some clinicians may not understand what immunochemistry is and what its role is in lung cancer diagnosis, prognosis and therapy. The purpose of this paper is to define immunochemistry, on the background of basic respiratory airway epithelial structure and cancer biology, and discuss its application in the diagnosis, treatment and determination of prognosis of lung cancer. Copyright © 2011 S. Karger AG, Basel Received: January 27, 2011 Accepted after revision: April 19, 2011 Published online: July 6, 2011 Oncology Aldoph B. Nanguzgambo Room 3013, 3rd Floor Clinical Building Faculty of Health Sciences, University of Stellenbosch Francie van Zil Drive, Tygerberg, Cape Town 7505 (South Africa) Tel. +27 21 938 9423, E-Mail abnanguzgambo @ yahoo.co.uk © 2011 S. Karger AG, Basel 0030–2414/11/0804–0247$38.00/0 Accessible online at: www.karger.com/ocl D ow nl oa de d by : 54 .7 0. 40 .1 1 11 /1 9/ 20 17 2 :5 9: 58 P M Nanguzgambo /Razack /Louw /Bolliger Oncology 2011;80:247–256 248 Respiratory Airway Epithelial Cells and Lung Cancer
منابع مشابه
Immunochemistry and lung cancer: application in diagnosis, prognosis and targeted therapy.
Immunochemistry is now an established ancillary technique in lung cancer diagnosis. Not only does it help in supporting the morphological diagnosis of malignancy, but its role now extends to the determination of cell lineage, ascertaining the primary site of tumour origin and contributing to decisions on prognosis and treatment. Early detection and confirmation of lung cancer facilitate early t...
متن کاملImmunochemistry and Lung Cancer: Application in Diagnosis, Prognosis and Targeted Therapy
Immunochemistry is now an established ancillary technique in lung cancer diagnosis. Not only does it help in supporting the morphological diagnosis of malignancy, but its role now extends to the determination of cell lineage, ascertaining the primary site of tumour origin and contributing to decisions on prognosis and treatment. Early detection and confirmation of lung cancer facilitate early t...
متن کاملImmunochemistry and Lung Cancer: Application in Diagnosis, Prognosis and Targeted Therapy
Immunochemistry is now an established ancillary technique in lung cancer diagnosis. Not only does it help in supporting the morphological diagnosis of malignancy, but its role now extends to the determination of cell lineage, ascertaining the primary site of tumour origin and contributing to decisions on prognosis and treatment. Early detection and confirmation of lung cancer facilitate early t...
متن کاملImmunochemistry and Lung Cancer: Application in Diagnosis, Prognosis and Targeted Therapy
Immunochemistry is now an established ancillary technique in lung cancer diagnosis. Not only does it help in supporting the morphological diagnosis of malignancy, but its role now extends to the determination of cell lineage, ascertaining the primary site of tumour origin and contributing to decisions on prognosis and treatment. Early detection and confirmation of lung cancer facilitate early t...
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